منابع مشابه
Endothelium-Dependent Attenuating Effect of Trigonella foenum-graecum on the Contractile Vascular Reactivity of Diabetic Rats
The present study was undertaken to determine whether two-month treatment of streptozotocin (STZ)-diabetic rats with aqueous leaf extract of Trigonella foenum-graecum (TFG 200 mg/kg i.p.) could improve thoracic aortic responsiveness and to evaluate its endothelium dependency. For this purpose, vascular responses to KCl and noradrenaline (NA) were measured. Diabetic state significantly increased...
متن کاملThe Vascular Endothelium in Diabetes
Key Points • The endothelium is a key participant in the homeostasis of the vessel wall. • Nitric oxide (NO) plays a key role in regulating healthy vascular function. • Reduced local NO bioavailability is a characteristic hallmark of vascular endothelial dysfunction. • Endothelial dysfunction is chiefly driven by oxidative stress and inflammation. • A number of techniques for assessing endothel...
متن کاملVascular gp91 Beyond the Endothelium
present compelling evidence for conventional gp91containing NAD(P)H oxidase in the vascular endothelium and for the functional involvement of gp91 in endothelial cell NAD(P)H oxidase superoxide anion (O2) production and aberrant endothelium-dependent relaxation. Many studies have implicated reactive oxygen species in the impairment of endothelium-dependent vascular responses.2–10 Since their in...
متن کاملEpigenetics of the vascular endothelium.
Classical models of transcription in vascular endothelial cells, specifically the cis/trans paradigm, have limitations. For instance, how does the environment have chronic effects on gene expression in endothelial cells after weeks or years? When an endothelial cell divides, how is this information transmitted to daughter cells? Epigenetics refers to chromatin-based pathways important in the re...
متن کاملMalaria and Vascular Endothelium
Involvement of the cardiovascular system in patients with infectious and parasitic diseases can result from both intrinsic mechanisms of the disease and drug intervention. Malaria is an example, considering that the endothelial injury by Plasmodium-infected erythrocytes can cause circulatory disorders. This is a literature review aimed at discussing the relationship between malaria and endothel...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1993
ISSN: 0003-4932
DOI: 10.1097/00000658-199321850-00003